![]() However, no studies have compared the two statin treatment strategies. On the other hand, the treat-to-target strategy makes customized treatment possible and reduces the side effects of the high statin-intensity strategy. However, individual response to statin can vary, and the long-term use of high-intensity statin can result in side effects, including muscle pain, liver damage, and diabetes. The high-intensity statin strategy is convenient as it does not need to control statin intensity. The other is to use high-intensity statin regardless of LDL-C levels, One is the “treat-to-target” strategy, which sets LDL-C treatment targets and controls statin intensity according to them. (From left) Professors Hong Myeong-ki, Hong Sung-jin, and Lee Yong-joon (Courtesy of Severance Hospital)Ī research team led by three Severance Hospital cardiologists - Professors Hong Myeong-ki, Hong Sung-jin, and Lee Yong-joon – said Friday that a treatment that controls statin intensity to suit low-density lipoprotein cholesterol (LDL-C) treatment targets in atherosclerotic cardiovascular diseases is equally effective to high-intensity maintenance therapy while lowering statin-related side effects.Ĭardiologists usually use two strategies in administering statin to prevent secondary complications and lower LDL cholesterol in patients with atherosclerotic cardiovascular disease. A Severance Hospital research team has found that a treatment that controls statin intensity to suit low-density lipoprotein cholesterol (LDL-C) treatment targets in atherosclerotic cardiovascular diseases is equally effective to high-intensity maintenance therapy while lowering statin-related side effects.
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